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Biotechnology

California Occupational Guide Number 2007
1996 (Archived August 2003)

Why are these jobs Emerging?

They fit the categories of:

  --  New occupations created by technological innovations
  --  Existing occupations requiring new high technological skills
  --  New occupations created as offshoots of existing occupations

"Biotechnology is a promising field that is predicted to be one of the
pivotal forces of the 21st Century.  Today it is saving lives through the
development of breakthrough drugs and improving the quality of life
with new agriculture and environmental products."

                                      Biotechnology Industry Organization


TABLE OF CONTENTS

Highlights                                                          Page  1
Introduction                                                              2
Biotechnology                                                             3
          More about Biotechnology                                        3
          California                                                      3
          The Industry                                                    4
          Stages of Production                                            5
Occupational Clusters and Categories                                      7
           Alphabetical Index of Biotechnology Occupations                8
           Research and Development                                       9
           Clinical Research                                             12
           Manufacturing and Production                                  15
           Quality Systems                                               24
           Information Systems                                           28
Preparing for Jobs in Biotechnology                                      29
Related  Academic Programs in California Community Colleges              31
Sources of Additional Information                                        33
Bibliography                                                             34


HIGHLIGHTS

There are over 1,300 companies engaged in biotechnology in the United States 
and over 30 percent of them are located in California.

In 1992, there were about 80,000 people employed nationwide in the 
biotechnology industry.  By the end of the decade over 200,000 will be 
employed in biotechnology according to the Biotechnology Industry 
Organization.  

In California, some have predicted that up to 20,000 new jobs will be created
in biotechnology companies by the year 2000.  Most of these jobs will be in 
San Diego, Orange and Los Angeles Counties and in the San Francisco Bay Area.

Most growth is expected in the areas of diagnostics and therapeutics since 
Research and development activity and manufacturing have been particularly 
high in these areas compared to other sectors of the biotechnology industry.

High turnover and attrition in some companies could mean thousands of job 
openings during the 1990s.

Opportunities exist for workers who have completed their associate and 
bachelor degrees with emphasis in the biological and laboratory sciences or 
technology.


INTRODUCTION

These are examples of a few of the many products and processes developed 
through biotechnology:

Tomatoes that can ripen on the vine, stay fresh while they are shipped to 
distant produce markets, and still taste good without falling apart in your 
hands.

Crops that can grow in the previously infertile acid soil of a section of 
Latin America.  This area covers about 800,000 square miles or slightly 
larger than the size of Mexico.

New drugs which used in combination with existing ones will lower the amount 
of acquired immune deficiency syndrome (AIDS) viruses in blood.

An human immunodeficiency virus (HIV) testing kit that can be used in the 
home.

Potential treatment for Lou Gehrig's disease.

Biological processes that will alter a tree's growth cycle so that it can be 
more easily turned into paper while significantly reducing the paper mill's 
energy and chemical consumption.

Methods used to capture and convict criminals by identifying an individual's 
unique deoxyribonucleic acid (DNA) characteristics (genetic profiling).

Corn which produces its own natural pesticides.

One common definition of biotechnology is "the use of living cells and 
materials to develop and manufacture products used in improving human health,
animal health, agriculture, and the environment."  Since this definition is 
quite broad, additional examples on the following pages may help provide a 
better understanding of biotechnology, its origins, and the industry's 
current status in California.


BIOTECHNOLOGY

Biological methods such as fermentation, cross-breeding, and hybridization 
have been long used for producing wine, bread and beer, the breeding of 
animals, and the improvement of farm crops.  Scientists suspected for years 
that nucleic acid in cells carried a major role in cell inheritance, but it 
was not until the early 1940s that they were able to prove by experiments at 
the Rockefeller Institute that DNA has a direct role in passing genetic 
information in all living cells.  Biotechnology was born in the 1950s with 
the discovery of the structure and function of the DNA molecule by 
James Watson and Francis Crick at the University of Cambridge in England.
The DNA molecule contains the genetic information which governs the 
transmission of hereditary traits from one generation to the next of most 
living systems.  With this knowledge the scientists were able to unlock the 
mystery of how genetic information was encoded and  transmitted.  The 
resulting development of molecular and cellular biology has helped create the
 tools and technologies for altering genetic information in plants and 
animals using living cells.  

More about Biotechnology

Biotechnology also can be seen as the commercial application of biological 
knowledge and modern technologies to manufacture products which are used in 
agriculture, medical treatment and diagnosis, environmental cleanup, 
cosmetics, and many other areas.

More specifically, scientists have developed genetically engineered drugs to 
dissolve blood clots to prevent heart attacks.  The development of human 
insulin to replace insulin from pigs and cows in the late 1987s was 
considered one of the first major accomplishments of biotechnology.
Genetically engineered proteins are used to attack cancer cells, and other
substances are used to halt the growth of cells in leukemia patients.

Medical diagnosis has been advanced by  products such as monoclonal 
antibodies which are being used to detect pregnancy, various kinds of cancer,
and the presence of sexually transmitted diseases.  In the area of animal 
health an example of a biotechnology application is the development of a 
gene-spliced vaccine which is being used to control a rabies epidemic among
raccoons in the Northeast and Florida.

California

Over 32 percent of the 1,300 biotechnology firms in the United States are 
located in California.  These 400 companies plus nonprofit Research 
institutions employ approximately from 50,000 to 65,000 workers.  Recent 
estimates project a national biotechnology workforce of over 105,000 by the 
year 2000, and the biotech workforce in California could increase by at least
12,000 to 20,000 new jobs by the end of the 1990s.

The Bay Area Bioscience Center reported in Spring of 1993 that California had
over 750 bioscience companies, with over 350 in the Bay Area, approximately 
150 in San Diego County, 200 in the Greater Los Angeles area, and about 25 
in the Davis/Sacramento region.  Its definition of bioscience includes not 
only firms which use biotechnology to develop new products and services but 
also those which develop biotechnology applications, industry suppliers of 
technical products such as computer software and instrumentation, and 
universities and Research institutions.

All of the major biotechnology centers have several characteristics in 
common: they have major Research universities and leading Research 
institutions; an abundance of talent at all levels of bioscience and 
biotechnology; a large reservoir of industrial experience such as in 
computers, pharmaceuticals, medical devices, and electronics; and the 
availability of funds to invest in high technology. 

The path a product takes from conception to the manufacturing stage usually 
takes many years because of basic Research and development, clinical testing,
and regulatory factors.  As a result, a bioscience company will likely incur 
enormous costs before its product reaches the manufacturing stage.  Until 
recently, the available pool of talent has been sufficient to meet the needs 
of the companies; however, it has become clear that since the early 1990s 
there has been a dramatic expansion of the bioscience industry, and there is 
a serious shortage of workers who have the required skills and education.

Currently, there are hundreds of pharmaceutical companies that have several 
hundred products created through biotechnology methods that are approaching 
the end of the Research and development phase.  Most of these products that 
successfully pass clinical trials and meet regulatory approvals will find 
their way to the marketplace.  The result will be a rapid increase in 
production and commercial manufacturing activities which will create 
thousands of job opportunities for prospective workers who meet the 
educational and  work experience requirements.

The Industry 

Identifying the different types of companies within the biotechnology 
industry can be difficult.  Some companies are created for the purpose of 
exploring biotechnology, while others use the process of biotechnology to 
manufacture pharmaceutical, agricultural, environmental and food products.
The types of biotechnology companies can be divided in several ways.  The 
Biotechnology Industry Organization separates the industry into the 
following areas: therapeutic, human diagnostics, supplier, chemical-
environmental, and agricultural.  Other industry organizations have added the
categories of energy production, medical devices, biopharmaceutical, 
veterinary, and various combinations of these categories.

The human therapeutics and diagnostics sectors have, by far, the greatest 
amount of activity, involving 65 to 70 percent of the biotechnology 
companies in the United States.  About 17 percent of the companies are 
engaged in producing equipment and supplies for bioscience Research and 
manufacturing.

The following are examples of types of activities taking place in five 
segments of the biotechnology industry and a brief description of the stages 
of production for a typical product.

Human Diagnostics:  Companies are engaged in producing medical devices to 
test for genetic and infectious diseases.  Genetic diseases, such as Sickle-
cell anemia, Cystic Fibrosis, and Alzheimer's disease, are those in which 
heredity plays a major role.  Infectious diseases, like human 
immunodeficiency virus (HIV), hepatitis B, and influenza, are those which are
caused by person-to-person exposure to bacteria or a virus.  Examples of 
diagnostic products are tests for blood screening for various diseases, 
materials and equipment used to analyze samples of blood and other bodily 
fluids, and tools to locate defective genes which cause hereditary diseases. 

Human Therapeutics:  Companies produce materials and pharmaceuticals to treat 
illnesses.  Therapeutic products include genetically engineered proteins used 
to lessen the effects of heart attacks and to slow or halt the growth of 
cancer cells of patients with leukemia.  Several companies are developing 
vaccines to treat AIDS and the diseases that are associated with AIDS.
Genetically engineered growth hormones are being used to treat dwarfism, 
and other genetically engineered materials are commonly used to treat anemia 
and organ transplant rejection.  Other diseases which are being treated or 
prevented through biotechnology include other forms of cancer, diabetes, and 
hemophilia. 

Agricultural & Veterinary:  Animal scientists have developed methods for 
breeding and raising farm animals so that they can be more efficiently raised
resulting in lower production costs.  Products of biotechnology include 
treatments and tests for farm animal diseases such as those found in cattle, 
sheep, and pigs.  Vaccines have been developed to prevent diseases such as 
foot-and-mouth disease in cattle, tapeworm in sheep, and dozens of other 
types of bacterial infections and viruses found in animals throughout the 
world.

Food/Chemical:  Companies are marketing products developed by scientists 
which detect food-borne microbes and toxins and test for chemical 
contamination.  Genes have been developed to be added to food crops to 
provide natural protection against insect pests.  Genetically engineered 
enzymes have been used in producing high fructose corn syrup which is used 
as a sweetener in a large number of prepared foods and beverages and in 
producing enzymes for making cheese.  Scientists are also working on plants 
which are drought and frost resistant.

Environmental:  Bacteria have been developed to clean up oil spills and 
chemical leaks from storage tanks by rendering the toxic materials or 
hazardous substances harmless.  Experts have said that this area of 
biotechnology offers great promise.  Bacteria are also used in cleaning waste 
water of harmful chemicals and in detoxifying or reducing industrial waste 
at its source.

Stages of Production

Research and Development:  A company's first steps in producing and marketing
a new product involves the process of Research and development (R&D).
During R&D, small scale experiments take place as scientists and laboratory 
staff work together to develop new products which offer promise.  At this
point in time, the number of staff is usually quite small.  Typically, an R&D
team would consist of scientists, Research associates, laboratory assistants 
and technicians.  Because Research is the primary function of the 
organization, at this point, most lead scientists possess Ph.D.s while other 
Research associates and technical support staff have bachelor's and master's 
degrees.

Research and Development is a lengthy process (lasting as long as one year 
or more).  Researchers concentrate on new discoveries, and scientists and 
technical staff engage in process development and the scaling up of 
production resources to conduct full-scale manufacturing.

R&D uses far fewer workers than manufacturing.  Where R&D employs highly 
educated scientists, engineers, and support personnel, manufacturing does 
not share the same educational requirements.

Actual production begins at the R&D stage when small amounts of the product 
are needed for testing and various experiments, including human clinical 
trials.  Production, at this point, includes cell culture and fermentation, 
where the desired cells and cell parts are grown; primary recovery where the 
product is captured for further processing; and the purification and 
packaging of the product into bulk form.  

A company must then prove to the U.S. Food and Drug Administration (FDA) 
that its product is safe and effective.  After receiving approval from the 
FDA, it may begin testing the drug in clinical trials.  During this phase, 
production of the product  takes place in a pilot plant or in an expanded 
section of the laboratory.  Up to fifty people may be employed to operate 
this small manufacturing facility and to conduct clinical Research.

Before receiving FDA approval for manufacturing and marketing, a company 
must establish that its product is safe and effective and can be 
manufactured consistently, and the production processes adheres to FDA and 
U.S. Environmental Protection Agency (EPA) regulations relating to Good 
Manufacturing Practices (GMPs).

As many as fifteen years may pass from the time a product is first 
conceived, developed, and tested before it finally receives regulatory 
approval from the FDA for manufacturing. 

Manufacturing and Production:  Upon receiving permission from the FDA, the 
manufacturing process is expanded to produce large quantities of product 
which may include creating a manufacturing facility.  Additional staff are 
hired for the manufacturing process including technicians, operators of 
production and packaging equipment, quality systems personnel, and workers 
involved with product distribution.

At this stage of operation, the company is hiring more technical personnel 
with bachelor's and master's degrees and fewer with Ph.D.s.  At the time 
employment opportunities increase for technicians who have associate's 
degrees from community colleges as well as for support staff with high 
school diplomas.


OCCUPATIONAL CLUSTERS AND CATEGORIES

The occupations described in the next section are typical of those found in 
the biotechnology industry.  For the purpose of this report, we are 
describing occupations which are technical in nature, jobs which can serve 
as stepping stones to technical positions, and jobs which require high 
school graduation or graduation from a college or university with a 
bachelor's or master's degree.  Jobs requiring Ph.D.s or which are in a 
company's administrative or sales organization are not included in this 
report.

Occupational descriptions are grouped by five major categories, all or 
some of which may be found in a biotechnology company: Research and 
Development, Clinical Research, Manufacturing and Production, Quality 
Systems, and Information Systems.  Since these job descriptions were derived 
from a number of industry sources, not all of the occupations may be found 
in any one given company, and some of the jobs described may have been 
combined with others in actual Research and development or manufacturing 
environments.  

Job Title:  These titles reflect jobs commonly found in a biotechnology 
company.

What They Do:  This is a brief job description illustrating an individual's 
responsibilities and job duties.

Skills/Knowledge:  These are examples of some of the major skills, knowledge,
and abilities necessary for a worker to successfully carry out the job.

Training Requirements:  These are the minimum educational and work 
experience requirements for the job described.  Years of experience required 
may be stated, for example, as "up to 2 years."  This means that employers 
may be willing to hire job candidates with no experience or may require up 
to two years of specified experience. 

Wage:  A wage range is usually cited.  The lower end of the wage range 
reflects the wages typically paid to entry-level workers.  The higher end of 
the wage range reflects the pay for those workers with two to three years of 
experience in the job described.  Wage data were obtained from industry 
reports or summaries of published wage surveys.

Occupational Codes:  This report includes, where possible, appropriate 
occupational codes from the Dictionary of Occupational Titles and the 
Occupational Employment System to provide a means of referencing other 
occupational materials. "DOT" refers to codes found in the Dictionary of 
Occupational Titles  (Fourth Edition, Revision 1).  "OES" codes are found in 
the Occupational Employment Statistics system.  "NA" indicates that codes 
were not found in either the DOT or OES system.


ALPHABETICAL INDEX OF BIOTECHNOLOGY OCCUPATIONS

Occupation                                                         Page No.

Animal Handlers                                                          12
Animal Technicians                                                       12
Aseptic Fill Assistants                                                  15
Aseptic Fill Research Associates                                         16
Aseptic Fill Technicians                                                 15
Assay Analysts                                                           16
Biochemical Development Engineers                                        17
Cell Culture & Fermentation                                              17
Cell Culture & Fermentation Research Associates                          18
Cell Culture & Fermentation Technicians                                  18
Clinical Research Associates                                             13
Data Entry Clerks                                                        13
Documentation Clerks                                                     24
Greenhouse Assistants                                                     9
Instrumentation/Calibration Technicians                                  19
Laboratory Assistants                                                     9
Laboratory Support Workers                                               10
Library Assistants                                                       28
Manufacturing Engineers                                                  19
Manufacturing Research Associates                                        20
Manufacturing Technicians                                                20
Microbiologists                                                          24
Plant Breeders                                                           10
Process Development Associates                                           21
Process Development Engineers                                            21
Production Planners                                                      22
Purification Assistants                                                  22
Purification Manufacturing Associates                                    23
Purification Technicians                                                 23
Quality Assurance Auditors                                               25
Quality Control Analysts                                                 25
Quality Control Engineers                                                26
Quality Control Inspectors                                               26
Research Associates (R&D)                                                11
Safety Specialists                                                       27
Scientific Programmer Analysts                                           28
Scientists                                                               11
Statisticians                                                            14
Technical Writers                                                        14
Validation Technicians                                                   27



                          Research AND DEVELOPMENT
                           GREENHOUSE ASSISTANTS

What They Do:  Greenhouse Assistants perform a variety of greenhouse Research 
tasks and experiments.  They may make detailed observations to detect 
horticultural or pest problems and take corrective action as needed. 
Greenhouse Assistants determine optimal cultural requirements and perform 
tasks to prevent insects and disease from inhabiting the plants.  They may 
collect, record, and analyze data and assist in the interpretation of 
results.  Assistants may also perform troubleshooting and maintenance of 
equipment.

Skills/Knowledge

  -- Attention to detail.
  -- Ability to understand and follow directions.
  -- Good written, oral and computer communication skills.

Training/Requirements

  -- High school diploma or associate degree or equivalent.
  -- Possess up to two years of greenhouse or plant experience.

Wage Range:  $21,000 - $32,000 per year

Occupational Codes

DOT:
Scientific Helper, 199.364-014

OES:
Physical Life Science Technicians, 245990



                          Research AND DEVELOPMENT
                            LABORATORY ASSISTANTS

What They Do:  Laboratory Assistants are responsible for performing a variety 
of tasks in the laboratory including weighing and measuring compounds and 
solutions, making detailed observations, analyzing data on experiments, and 
interpreting results.  They may also write experimental reports and 
summaries.  Assistants maintain laboratory equipment and inventories for 
laboratory equipment and supplies.  They may perform limited troubleshooting
and calibration of laboratory instruments and also care for and handle 
animals in animal laboratories.

Skills/Knowledge

  -- Attention to detail.
  -- Good oral, written and computer communication skills.
  -- Ability to follow and execute detailed instructions.
  -- Ability to understand regulatory procedures.
  -- Understanding of troubleshooting procedures.

Training/Requirements

  -- High school diploma or associate degree in the laboratory sciences.
  -- Have up to two years of laboratory experience.

Wage Range:  $17,000 - $29,000 per year

Occupational Codes

DOT:
Scientific Helper, 199.364-014

OES:
Physical Life Science Technicians, 245990



                           Research AND DEVELOPMENT
                          LABORATORY SUPPORT WORKERS

What They Do:  Laboratory Support Workers are responsible for washing and 
caring for glassware in the laboratory.  They distribute the equipment to 
work stations within the laboratory.  They operate and maintain the 
glass washing equipment and keep the work area clean and neat.  They may use 
the autoclave to sterilize glassware and other laboratory items and keep 
inventory of supplies.

Skills/Knowledge

  -- Ability to maintain accurate records.
  -- Good written and oral communication skills.
  -- Ability to understand and follow directions.

Training/Requirements

  -- High school diploma or associate degree or equivalent.
  -- Up to two years of work experience preferred.

Wage Range:  $12,000 - $21,000 per year

Occupational Codes

DOT:
Cleaner, Laboratory Equipment, 381.687-022  

OES:
Janitors, Cleaners, 670050



                          Research AND DEVELOPMENT
                                PLANT BREEDERS

What They Do:  Plant Breeders work with Research staff in designing, 
developing, executing, and carrying out plant breeding Research projects to 
develop and improve varieties of crops.  They work on projects to improve 
crop  characteristics such as size, yield, resistance to disease, weather, 
and insect pests.  The Breeder may use exotic germ plasm and work with 
various mating systems.  They integrate with biotechnology as needed to 
enhance selection methods and accelerate product development.

Skills/Knowledge

  -- Ability to maintain accurate records.
  -- Attention to detail.
  -- Good oral, written and computer communication skills.

Training/Requirements

  -- BS degree or equivalent.
  -- Up to two years of experience in plant breeding, agronomics and/or 
  -- training in plant breeding or plant science.

Wage Range:  $20,000 - $40,000 per year

Occupational Codes

DOT:
Plant Breeder, 041.061-082

OES:
Biological Scientists, 243080



                          Research AND DEVELOPMENT
                            Research ASSOCIATES

What They Do:  Research Associates in Research and Development are usually 
responsible for performing Research and laboratory tasks for projects and 
products in collaboration with others.  They assist in the design and 
execution of experiments and in the interpretation of the results of the 
scientific investigation.  Their work often requires the preparation of 
technical reports, protocols, summaries and analyses of data.  Research 
Associates may act as principal investigators in conducting their own 
experiments.

Skills/Knowledge

  -- Good oral, written and computer communication skills.
  -- Ability to maintain accurate records.
  -- Ability to read and understand relevant scientific literature.
  -- Strong observational and computational skills.

Training/Requirements

  -- BS or MS degree in a discipline such as biology, biochemistry, chemistry, 
     molecular biology, or biotechnology.
  -- Possess up to two years of laboratory experience with MS and two to five 
     years with BS.

Wage Range:  $25,000 - $45,000 per year

Occupational Codes

DOT:
Various biology and chemistry occupations

OES:
Biological Scientists,  243080
Chemists,               241050



                            Research AND DEVELOPMENT
                                  SCIENTISTS

What They Do:  Scientists perform similar tasks as Research Associates 
however they are expected to utilize a more detailed knowledge of scientific 
theory and applications and to apply this knowledge towards the development 
of new products and inventions and to solve complex Research problems.  The 
Scientist is usually responsible for designing and implementing scientific 
Research and development projects in conjunction with other Research staff.
They provide scientific guidance to staff and may supervise other Scientists 
and Research Associates.

Skills/Knowledge

  -- High degree of scientific creativity and technical proficiency.
  -- Excellent oral, written and computer communication skills.
  -- Ability to transfer scientific knowledge to practical applications.

Training/Requirements

MS degree in biological sciences or chemistry with up to five years of 
experience in a Research environment or Ph.D. in a scientific discipline 
with up to two years of experience.

Wage Range:  $40,000 - $65,000 per year

Occupational Codes

DOT:

Various biology and chemistry occupations

OES:
Biological Scientists, 243080
Chemists, 241050



                                CLINICAL Research
                                 ANIMAL HANDLERS

What They Do:  Animal Handlers are responsible for the daily care of 
laboratory animals.  They provide food and water to the animals and clean and 
disinfect their cages, racks, and pens.  Handlers examine the animals for 
signs of illness, provide grooming and baths, adjust the temperature and 
humidity of the animal quarters, and maintain records to comply with 
regulatory standards and operating procedures.

Skills/Knowledge

  -- Ability to monitor, restrain, handle, and care for laboratory animals.
  -- Attention to detailed instructions.
  -- Good oral, written and computer communication skills.
  -- Ability to maintain detailed records.

Training/Requirements

  -- High school diploma or equivalent with a scientific background.
  -- Possess up to two years of laboratory experience.

Wage Range:  $13,000 to $18,000 per year

Occupational Codes

DOT:
Animal Caretaker, 410.674-010

OES:
Animal Caretakers, except Farm, 790170



                               CLINICAL Research
                               ANIMAL TECHNICIANS

What They Do: Animal Technicians provide care for Research animals before 
and after surgery.  They check on their condition after surgery and maintain 
required records of their condition.  Technicians are also responsible for 
obtaining laboratory animals, supplies, carrying out preventative 
maintenance of laboratory equipment, and developing standard operating 
procedures for the handling and care of animals. In addition, they prepare 
the treatment rooms for surgery and assist in restraining the animal during 
examinations and inoculations.

Skills/Knowledge

  -- Ability to monitor, restrain, handle, and care for laboratory animals.
  -- Understand detailed instructions and procedures.
  -- Ability to maintain required laboratory records. 

Training/Requirements

  -- High school diploma or equivalent with a scientific background.
  -- Possess up to two years of laboratory experience.

Wage Range:  $16,000 - $23,000 per year

Occupational Codes

DOT:
Veterinary Technician, 079.361-014

OES:
Veterinary Technicians, 329510
Veterinary Assistants, 798060



                               CLINICAL Research
                         CLINICAL Research ASSOCIATES

What They Do:  Clinical Research Associates design, plan, and implement 
clinical Research projects.  They monitor the running of clinical trials at 
each trial site and collect pertinent biological data.  Research Associates 
are responsible for evaluating and analyzing clinical data and coordinating 
activities of associates to ensure compliance with technical guidelines and 
overall clinical objectives.  


Skills/Knowledge

  -- Knowledge and understanding of clinical terminology and operations.
  -- Attention to detail.
  -- Good organization and oral, written and computer communication skills.
  -- Understanding of regulatory practices.


Training/Requirements

  -- BS or MS degree in biological sciences or RN degree or equivalent.
  -- Possess up to two years experience in medical Research, pharmaceutical 
     Research, or nursing.

Wage Range:  $30,000 to $55,000 per year

Occupational Codes

DOT:  Not Available

OES:
Biological Scientists, 243080



                                CLINICAL Research
                                DATA ENTRY CLERKS

What They Do:  Data Entry Clerks are responsible for using a keyboard or 
other type of data entry device to enter clinical Research data into a 
computer statistical database.  They may operate on-line terminals, personal 
computers, and scanners.

Skills/Knowledge

  -- Ability to key enter data at a high speed and with accuracy.
  -- Good spelling and grammatical skills.
  -- Familiarity with technical language and terminology.


Training/Requirements

High school diploma or AA degree with training in word processing, data 
entry or some job experience.


Wage Range:  $11,000 to $25,000 per year

Occupational Codes

DOT:
Data Entry Clerk, 203.582-054

OES:
Data Entry Keyers, 560170



                              CLINICAL Research
                                STATISTICIANS 

What They Do:  Statisticians in clinical Research work with company staff in 
various departments to design, test, and implement statistical programs 
which process data generated from clinical trials.  They are responsible for 
planning data collection efforts, interpreting and evaluating the data 
produced, identifying trends and data relationships, and taking action to
correct data inconsistencies. 

Their data are usually presented in the form of computer generated tables, 
charts, graphs, and written reports.


Skills/Knowledge

  -- Understanding of clinical terminology and regulations relating to good 
  -- clinical practices.
  -- Good organization and oral, written and computer communication skills.
  -- Familiarity with technical language and terminology.

Training/Requirements

  -- BS or MS degree and above in mathematics or statistics.
  -- Possess up to two years experience in clinical Research.

Wage Range:  $25,000 to $45,000 per year

Occupational Codes

DOT:
Statistician, Applied, 020.167-026

OES:
Statisticians, 253120



                                CLINICAL Research
                                TECHNICAL WRITERS

What They Do:  Technical Writers write and edit laboratory procedure manuals, 
standard operating procedures, and other technical and administrative 
publications.  The Technical Writer edits and rewrites material in 
compliance with governmental regulatory and company standards and language 
and assists in developing documentation and materials for training,
reference, informational and other purposes.

Some Technical Writers specialize in Researching, writing and editing 
clinical reports for submission to regulatory agencies such as the Food and 
Drug Administration.

Skills/Knowledge

  -- Ability to write in coherent technical English.
  -- Understand clinical terminology.
  -- Familiarity with federal standards for technical reports and proposals.

Training/Requirements

  -- BS degree or equivalent.
  -- Have up to two years of experience in writing and editing technical 
  -- reports.

Wage Range:  $25,000 to $45,000 per year

Occupational Codes

DOT:
Writer, Technical Publications, 131.267-026

OES:
Technical Writers, 340050



                         MANUFACTURING AND PRODUCTION
                            ASEPTIC FILL ASSISTANTS

What They Do:  Aseptic Fill Assistants set up and operate equipment used to 
manufacture and package new and existing products.  Assistants weigh, 
measure, and check products to assure that they contain the correct 
proportion of specified ingredients.

Skills/Knowledge

  -- Ability to maintain accurate records.
  -- Familiarity with regulatory requirements and standard operating 
     procedures.
  -- Ability to use basic math to collect data and perform calculations.
  -- Ability to document processes and troubleshoot problems.

Training/Requirements

  -- High school diploma or associate degree in biotechnology or related 
  -- health sciences field.
  -- Up to two years of experience in sterile manufacturing environment is 
     preferred.

Wage Range:  $18,000 to $26,000 per year

Occupational Codes:  Not Available



                         MANUFACTURING AND PRODUCTION
                           ASEPTIC FILL TECHNICIANS

What They Do:  Aseptic Fill Technicians assist in setting up, operating, 
and maintaining production systems.  They may also be responsible for 
assisting in the packaging and distribution processes and in maintaining 
production equipment.

Skills/Knowledge

  -- Knowledge of manufacturing procedures and federal regulations pertaining 
     to manufacturing practices.
  -- Familiarity with process flow diagrams and statistical process control.
  -- Ability to select appropriate methods and procedures to solve technical
     problems.
  -- Perform effectively under stress or in emergencies.

Training/Requirements

  -- Associate degree in biological sciences or BS degree in a scientific 
     discipline.
  -- Possess up to 2 years experience.

Wage Range:  $21,000 - $32,000 per year

Occupational Codes:  Not Available



                            MANUFACTURING AND PRODUCTION
                          ASEPTIC FILL Research ASSOCIATES

What They Do:  Aseptic Fill Research Associates put company production 
procedures into practice.  They may assist in developing the processes to 
improve product yield and to reduce the costs in manufacturing systems 
relating to aseptic fill.

Research Associates may also be responsible for operating and troubleshooting 
packaging equipment and have responsibility for servicing the equipment. 

Skills/Knowledge

  -- Knowledge about how the production systems operate.
  -- Ability to suggest and develop improvements to the production system.
  -- Ability to select appropriate methods and procedures to solve technical 
     problems.
  -- Attention to detail.
  -- Knowledge of process flow diagrams, statistical process control, and 
     production scheduling.

Training/Requirements

  -- BS or MS degree in a biological science.
  -- Have up to two years of experience in aseptic fill in a manufacturing 
     environment.

Wage Range:  $24,000 - $55,000 per year

Occupational Codes:  Not Available



                         MANUFACTURING AND PRODUCTION
                                ASSAY ANALYSTS

What They Do:  Assay analysts perform assays and tests on tissue and cell 
cultures to evaluate the quality of the culture media.  They obtain and read 
standard protocols and procedures for testing.  Analysts prepare, maintain, 
and check cell cultures and tissues, reagents, and equipment prior to tests.
They must also document and record test results and assist in modifying 
assay procedures.

Skills/Knowledge

  -- Good oral, written, and computer communication skills.
  -- Ability to use basic math.
  -- Ability to follow formal procedures and instructions.
  -- Knowledge of procedures used in troubleshooting problems in the event of 
     equipment or test failure.
  -- Ability to document and report test results.
  -- Understand company quality control and quality assurance systems. 

Training/Requirements

  -- High school diploma or equivalent.
  -- Up to 2 years of experience in sterile manufacturing environment.

Wage Range:  Not Available

Occupational Codes:  Not Available



                          MANUFACTURING AND PRODUCTION
                        BIOCHEMICAL DEVELOPMENT ENGINEERS

What They Do:  Biochemical Development Engineers are responsible for the 
design and scaling up of processes, instruments, and equipment from the 
laboratory stages of development to the pilot plant and manufacturing process.
The engineer is also responsible for assisting manufacturing staff in solving 
problems related to production equipment and systems and for participating 
in the design of new manufacturing facilities and equipment.  In addition, 
the engineer develops and recommends new process formulas and technologies 
to achieve cost effectiveness and product quality.

Skills/Knowledge

  -- Good oral, written, and computer communication skills.
  -- Knowledge of pilot plant and manufacturing processes, manufacturing 
     facilities and equipment.

Training/Requirements

  -- BS degree in biological, chemical, or pharmaceutical engineering or 
     related discipline.
  -- Up to 2 years of experience in pharmaceutical processes or Research 
     product development. 

Wage Range:  Not Available

Occupational Codes

DOT:
Chemical Engineer, 008.061-018

OES:
Chemical Engineers, 221140



                        MANUFACTURING AND PRODUCTION
                  CELL CULTURE AND FERMENTATION ASSISTANTS

What They Do:  These Assistants support manufacturing staff in specific 
product-related operations in bacterial fermentation.  They operate and 
maintain production equipment used in bacterial fermentation such as 
bioreactors, cell harvest, and separation procedures.  They also weigh, 
measure, and check raw materials to assure proper ingredients and quantities 
and maintain records to comply with regulatory requirements.

Skills/Knowledge

  -- Good oral, written, and computer communication skills.
  -- Ability to follow formal procedures and instructions.
  -- Knowledge of procedures used in troubleshooting problems.
  -- Ability to document and report test results.
  -- Understand company quality control and quality assurance systems.

Training/Requirements

  -- High school diploma or associate degree in microbiology, cell biology in 
     biotechnology, or a health related field.
  -- Up to 2 years of experience in sterile manufacturing environment.

Wage Range:  $18,000 - $26,000 per year

Occupational Codes

DOT:
Fermenter Operator, 559.685-070
Laboratory Assistant, Culture Media,  559.384-010

OES:
Chemical Equipment Tenders, 929380
Biological, Agricultural, Food Technicians,  245020



                         MANUFACTURING AND PRODUCTION
                  CELL CULTURE AND FERMENTATION TECHNICIANS

What They Do:  Cell Culture and Fermentation Technicians are responsible 
for successfully completing all activities involved with cell cultures to 
maintain protein production levels in compliance with established production 
practices and procedures.  The technicians operate and maintain bioreactors 
used for monoclonal antibody/protein production.  They also assist in 
preparing production standards and procedures.

Skills/Knowledge

  -- Good oral, written, and computer communication skills.
  -- Attention to detail and sterile techniques.
  -- Knowledge of good manufacturing practices.

Training/Requirements

  -- Associate degree in biotechnology or biology or BS degree in biological 
     sciences or related health fields.
  -- Experience in sterile manufacturing environment.

Wage Range:  $21,000 - $32,000 per year

Occupational Codes:  Not Available



                         MANUFACTURING AND PRODUCTION
               CELL CULTURE AND FERMENTATION Research ASSOCIATES

What They Do:  Research Associates in cell culture and fermentation are 
responsible for operating and troubleshooting the operation of bioreactors.
They produce cell and virus concentrations and volumes according to 
production schedules and perform cell culture activities such as preparing 
the media and components, assisting in the development of production 
testing, harvesting cells and assuring that required production procedures 
are being followed. 

Skills/Knowledge

  -- Thorough knowledge of bioreactors.
  -- Ability to devise improvements to existing systems.
  -- Ability to design, execute and interpret prototype fermentation methods.

Training/Requirements

  -- BS or MS degree in microbiology or cellular biology.
  -- Up to 2 years of experience in pharmaceutical processes or Research 
     product development. 

Wage Range:  $24,000 - $42,000 per year

Occupational Codes:  Not Available



                          MANUFACTURING AND PRODUCTION
                    INSTRUMENTATION/CALIBRATION TECHNICIANS

What They Do:  Instrumentation/Calibration Technicians are responsible for 
maintaining, testing, calibrating, and repairing a variety of circuits, 
components, analytical equipment and instrumentation.  Technicians calibrate 
instrumentation, perform validation studies, and set up purchases of 
equipment.  They analyze test results, develop test specifications and 
electrical schematics, and maintain logs and required documentation. 
They may prepare technical reports with recommendations for solving 
technical problems.

Skills/Knowledge/

  -- Ability to accurately document findings.
  -- Ability to communicate effectively in writing, orally and electronically.
  -- Knowledge and ability to follow  regulations pertaining to good 
     manufacturing practices.
  -- Ability to troubleshoot equipment failure.

Training/Requirements

  -- High school diploma or AA degree in biotechnology or health related 
     fields.
  -- Scientific background and from one to two years of experience in quality 
     control systems.

Wage Range:  $22,000 to $35,000 per year

Occupational Codes

DOT:
Calibrator, 710.381-034

OES:
Workers, Precision, 899990



                           MANUFACTURING AND PRODUCTION
                             MANUFACTURING ENGINEERS

What They Do:  Manufacturing Engineers are responsible for developing, 
implementing, evaluating and maintaining manufacturing methods, operational 
sequences, and manufacturing processes.  They work with engineering 
department staff to coordinate the release of new products, estimate 
manufacturing costs, determine time standards and recommend production 
requirements for new and existing product lines. 

Skills/Knowledge

  -- Good oral, written, and computer communication skills.
  -- Knowledge of product design and materials.
  -- Knowledge of manufacturing processes, equipment capabilities, and 
     production methods.
  -- Knowledge and understanding of quality control/assurance standards.

Training/Requirements

  -- BS degree in a scientific discipline or equivalent.
  -- Up to 2 years experience in Research product development or in 
     manufacturing.

Wage Range:  $32,000 - $56,000 per year

Occupational Codes

DOT:
Manufacturing Engineer, 012.167-042 

OES:
Industrial Engineers, 221280



                         MANUFACTURING AND PRODUCTION
                       MANUFACTURING Research ASSOCIATES

What They Do:  Manufacturing Research Associates are responsible for 
assisting in the implementation of production procedures to improve 
manufacturing processes.  The Research Associate may also maintain 
production equipment and be involved in the packaging and distribution 
processes.

Skills/Knowledge

  -- Good oral, written, and computer communication skills.
  -- Detailed knowledge of manufacturing systems.
  -- Knowledge of good manufacturing practices and attention to detail.
  -- Ability to identify and devise methods to improve existing systems.
  -- Good computational skills.

Training/Requirements

  -- BS or MS degree in biological sciences or in other scientific discipline.
  -- Up to two years of experience in a manufacturing environment.

Wage Range:  $22,000 to 40,000 per year

Occupational Codes:  Not Available



                         MANUFACTURING AND PRODUCTION
                          MANUFACTURING TECHNICIANS

What They Do:  Manufacturing Technicians operate and maintain equipment 
used in the manufacturing and packaging of products.  Technicians are 
responsible for implementing and coordinating production in the 
fermentation, purification and septic fill processes.  They weigh, measure 
and check raw materials, and ensure that the manufactured batches contain 
he proper amount and mix of ingredients.

Skills/Knowledge

  -- Good oral, written, and computer communication skills.
  -- Ability to understand detailed instructions.
  -- Knowledge of good manufacturing practices.

Training/Requirements

  -- HS diploma or equivalent at the entry level.
  -- BS or MS degree in biological sciences.
  -- Up to 2 years of experience in manufacturing. 

Wage Range:  $18,000 - $33,000 per year

Occupational Codes:  Not Available



                            MANUFACTURING AND PRODUCTION
                           PROCESS DEVELOPMENT ASSOCIATES

What They Do:  Process Development Associates implement procedures to 
optimize and improve manufacturing processes.  They assist in developing 
production processes which improve product yield and reduce production 
costs.  Processes may be in fermentation, purification, and aseptic fill 
areas.  Associates may be also responsible for Researching, developing, and 
implementing new methods and technologies to improve production.

Skills/Knowledge

  -- Good oral, written, and computer communication skills.
  -- Attention to detail essential.
  -- Detailed knowledge of manufacturing processes, equipment capabilities, 
     and production methods.

Training/Requirements

  -- BS or MS degree in biosciences, other scientific disciplines or in 
     engineering.
  -- Up to 2 years experience in manufacturing.

Wage Range:  $22,000 - $38,000 per year

Occupational Codes

DOT:
Production Engineer, 012.167-046

OES:
Industrial Engineers, 221280



                          MANUFACTURING AND PRODUCTION
                          PROCESS DEVELOPMENT ENGINEERS

What They Do:  Process Development Engineers design, develop, modify and 
enhance existing manufactured products and manufacturing processes.  Specific
tasks vary depending on the type of process under consideration, for 
example, assignments may involve electrical, mechanical, or chemical 
engineering.  Engineers may be responsible for contacts with outside vendors 
and for the administration of contracts.

Skills/Knowledge

  -- Ability to suggest and develop improvements to the production system.
  -- Familiarity with regulatory requirements and standard operating 
     procedures.

Training/Requirements

  -- BS or MS degree in the biosciences or in electrical, mechanical, or 
     chemical engineering.
  -- Up to 2 years of related experience.

Wage Range:  $25,000 - $53,000 per year

Occupational Codes

DOT:
Chemical Engineer, 008.061-018
Electrical Engineer, 003.061-010
Mechanical Engineer,  007.061-014

OES:
Chemical Engineers, 221140
Electrical Engineers, 221260
Mechanical Engineers, 221350



                         MANUFACTURING AND PRODUCTION
                             PRODUCTION PLANNERS

What They Do:  Production Planners plan, schedule, and coordinate all of 
the activities throughout the manufacturing process.  They draft schedules 
for each operational step, assure that materials are available, and 
determine that all production activities are in place to meet expected 
completion and shipping dates.  Planners work closely with staff in 
production, quality control, customer service, and marketing and sales to 
assure that production schedules can be met and that the finished products 
are meeting company standards and customer needs. 

Skills/Knowledge

  -- Possess good written, oral and computer communication skills.
  -- Ability to analyze processes in detail. 
  -- Ability to select appropriate methods and procedures to solve technical 
     problems.
  -- Perform effectively under stress or in emergencies.

Training/Requirements

  -- BS degree or equivalent.
  -- Possess up to 2 years of manufacturing experience.

Wage Range:  $21,000 - $31,000 per year

Occupational Codes

DOT:
Production Planner, 012.167-050

OES:
Industrial Engineers-except Safety, 221280



                      MANUFACTURING AND PRODUCTION
                         PURIFICATION ASSISTANTS 

What They Do:  Purification Assistants assist technicians in setting up 
and maintaining equipment used in protein purification and in the 
manufacturing of final products.  They also assist in the preparation of 
materials used in the purification process.  Purification Assistants also 
check, weigh, and measure batches of manufactured materials to assure 
that they contain the correct ingredients and proper amounts.  This is 
usually an entry level position involving primarily routine work assignments.

Skills/Knowledge

  -- Ability to understand and follow instructions.
  -- Knowledge of and adherence to good manufacturing practices, regulatory 
     requirements, and company production policies.
  -- Ability to take and maintain detailed records.

Training/Requirements

  -- HS diploma or associate degree in a bioscience or health field.
  -- Have up to two years of experience in sterile manufacturing.

Wage Range:  $18,000 - $26,000 per year

Occupational Codes:  Not Available



                      MANUFACTURING AND PRODUCTION
                  PURIFICATION MANUFACTURING ASSOCIATES

What They Do:  Purification Manufacturing Associates are responsible for 
implementing improvements to existing purification systems.  They may also 
assist in developing processes to reduce  production costs while improving 
he final product.  Associates may operate purification equipment and have 
responsibility for troubleshooting and maintaining this equipment.

Skills/Knowledge

  -- Ability to maintain accurate records.
  -- Familiarity with regulatory requirements and standard operating 
     procedures.
  -- Detailed knowledge of purification systems.
  -- Ability to document processes and diagnose problems. 

Training/Requirements

  -- BS or MS in biochemistry or other scientific discipline.
  -- Have up to two years of related experience.

Wage Range:  $27,000 - $42,000 per year

Occupational Codes:  Not Available



                       MANUFACTURING AND PRODUCTION
                         PURIFICATION TECHNICIANS 

What They Do:  Purification Technicians set up, operate and maintain the 
equipment used in protein purification.  They prepare buffers used in the 
purification process and perfume in-process testing.

Skills/Knowledge

  -- Knowledge of manufacturing procedures and federal regulations relating 
     to manufacturing practices.
  -- Ability to maintain accurate and detailed records.

Training/Requirements

  -- Associate degree in laboratory sciences or BS in biotechnology or related 
     scientific field.
  -- Possess up to 2 years experience preferably in sterile manufacturing.

Wage Range:  $21,000 - $32,000 per year

Occupational Codes:  Not Available



                             QUALITY SYSTEMS
                           DOCUMENTATION CLERKS

What They Do:  Documentation Clerks are responsible for maintaining the 
company's documentation system requirements such as standard operating 
procedures and other required documentation. They audit documentation 
manuals to assure that they are accurate and current and maintain a filing 
system of all master documents.

Skills/Knowledge

  -- Good written, oral and computer communication skills.
  -- Ability to maintain and locate documents and records.
  -- Ability to work independently. 

Training/Requirements

  -- High school diploma or associate degree.
  -- Up to two years of experience in documentation or quality control 
     or quality assurance.

Wage Range:
$20,000 to $30,000 per year

Occupational Codes

DOT:
File Clerk I, 206.387-034

OES:
File Clerks, 553210 



                              QUALITY SYSTEMS
                              MICROBIOLOGISTS

What They Do

Microbiologists develop and carry out chemical, physical and biochemical 
tests to study microscopic organisms, such as bacteria and viruses, found 
in samples of raw materials used in production and in samples of 
in-process and finished products. Using optical and electron microscopes, 
chromatographic equipment, spectrophotometers, amino acid analyzers, and 
other equipment to examine microorganisms to ensure that company and 
regulatory quality standards are being met.  They are also responsible 
for documenting the results of microbiological tests.

Skills/Knowledge

  -- Ability to work independently and in work groups and teams.
  -- Good written and oral communication skills.
  -- Knowledge and understanding of company, industry, and regulatory 
     standards.
  -- Ability to carry out detailed tasks requiring high degrees of 
     accuracy.

Training/Requirements

  -- BS or MS degree in microbiology.

Wage Range:
$26,000 to $47,000 per year

Occupational Codes

DOT:
Microbiologist, 041.061-058

OES:
Biological Scientists, 243080



                             QUALITY SYSTEMS
                         QUALITY ASSURANCE AUDITORS

What They Do

Quality Assurance Auditors perform audits of the production and quality 
control departments to determine if these organizational units are 
adhering to regulatory requirements on good manufacturing practices and 
are complying with company specifications and standards.  

Skills/Knowledge

  -- Ability to understand regulatory standards.
  -- Good organizational, computational and communication skills.
  -- Ability to maintain detailed records.

Training/Requirements

  -- BS degree in the biosciences or another scientific discipline.
  -- Up to two years of experience in biological or pharmaceutical 
     manufacturing.

Wage Range:
$26,000 to $40,000 per year

Occupational Codes

NA



                                 QUALITY SYSTEMS
                             QUALITY CONTROL ANALYSTS

What They Do

Quality Control Analysts conduct routine and non-routine analysis of raw 
materials and formulations which are in-process or finished according to 
standard operating procedures.  They compile data for the documentation 
of testing procedures and prepare reports and review data to determine 
if products are being produced in accordance with specifications.  They 
are also responsible for revising and updating company standard operating 
procedures and may calibrate and maintain laboratory equipment.

Skills/Knowledge

  -- Knowledge of statistical flow diagrams and process flow diagrams.
  -- Familiarity with regulations pertaining to good manufacturing and good 
     laboratory practices.

Training/Requirements

  -- BS or MS degree in biological sciences or another scientific discipline.
  -- Possess up to two to five years of experience preferably in a Research 
     environment in chemistry or biochemistry.

Wage Range:
$26,000 - $40,000

Occupational Codes

DOT:
Quality Control Technician, 012.261-014

OES:
Physical, Life Science Technicians, NEC,  245990



                              QUALITY SYSTEMS
                          QUALITY CONTROL ENGINEERS

What They Do:  Quality Control Engineers develop, apply and maintain 
quality control standards for processing materials into partially finished 
or finished products. Engineers design and implement methods and procedures 
for inspecting, testing, and evaluating the precision and accuracy of the 
production equipment and equipment used in the testing and inspection.  
They prepare documentation for inspection, testing procedures to assure 
that products  comply with company and regulatory practices. Engineers may 
also conduct company training or supervise quality control efforts.

Skills/Knowledge

  -- Knowledge of statistical flow diagrams and process flow diagrams.
  -- Familiarity with regulations pertaining to good manufacturing and good 
     laboratory practices.

Training/Requirements

  -- BS or MS degree in engineering or the biological sciences.
  -- Possess up to two to five years of quality control experience.

Wage Range:
$30,000 to $50,000 per year

Occupational Codes

DOT:
Quality Control Engineer, 012.167-054

OES:
Industrial Engineer, except Safety, 221280



                               QUALITY SYSTEMS
                           QUALITY CONTROL INSPECTORS

What They Do:  Quality Control Inspectors are responsible for performing a 
variety of inspections, checks, tests, and sampling procedures on raw 
materials, materials in-process, and finished products to be sent to a 
microbiologist or Quality Control Analyst for further analysis.  They 
document their findings for other staff to evaluate. They also monitor the 
operation of critical equipment and instrumentation and write and revise 
inspection procedures and inspection checklists.

Skills/Knowledge

  -- Ability to accurately document findings.
  -- Ability to communicate effectively in writing, orally and by computer.
  -- Knowledge and ability to follow  regulations pertaining to good 
     manufacturing practices.
  -- Ability to troubleshoot equipment failure.

Training/Requirements

  -- High school diploma or associate degree in biotechnology or health 
     related fields.
  -- Scientific background and from one to two years of experience in 
     quality control systems.

Wage Range:
$22,000 to $35,000 per year

Occupational Codes

DOT:
Quality Control Technician  012.261-014

OES:
Physical, Life Science Technicians, NEC,       245990



                              QUALITY SYSTEMS
                             SAFETY SPECIALISTS

What They Do:  Safety Specialists develop, implement, and monitor 
industrial safety programs. They inspect plant areas on a regular basis to 
ensure compliance with federal and state occupational and safety 
regulations. They evaluate equipment and raw materials for safety and 
monitor and perform tests to determine employee exposure to toxic materials, 
noise and other hazards.  Safety Specialists may be responsible for 
providing employee training in hazardous waste collection and disposal.

Skills/Knowledge

  -- Thorough understanding of federal and state industrial safety 
     regulations and industry and professional standards. 
  -- Good organization and oral, written, and computer communication skills.
  -- Ability to accurately document and report test results and to take 
     appropriate corrective action. 

Training/Requirements

  -- BS degree or equivalent.
  -- Possess up to two years of related experience.

Wage Range:
$20,000 to $36,000 per year

Occupational Codes

DOT:
Safety Inspector, 168.264-014

OES:
Compliance Officers and Enforcement Inspectors--except Construction, 219100



                              QUALITY SYSTEMS
                           VALIDATION TECHNICIANS

What They Do:  Validation Technicians develop, perform and prepare test 
procedures and standards to determine and ensure that products are being 
manufactured according to regulatory standards, company specifications and 
validation requirements. They compile and analyze validation data, prepare 
reports and recommend changes and improvements in manufacturing procedures. 
They also maintain validation records and data files. Validation technicians 
may be responsible for troubleshooting manufacturing problems and developing 
solutions.

Skills/Knowledge

  -- Good documentation and computational skills.
  -- Understanding of regulations pertaining to good manufacturing practices.
  -- Good organization and oral, written, and computer communications skills.

Training/Requirements

  -- High school diploma or associate degree in a biotechnical or related 
     health sciences field.
  -- Have up to two years of experience in a sterile manufacturing 
     environment.

Wage Range:
$25,000 to $40,000 per year

Occupational Codes

NA



                                INFORMATION SYSTEMS
                                 LIBRARY ASSISTANTS

What They Do:  Library Assistants locate and order articles and 
publications requested by library users.  These materials may be in the form 
of books, periodicals, microfiche, audio and video tapes, computer 
diskettes, and other electronic media.  They perform special data collection 
projects as requested and are responsible for conducting on-line computer 
searches of scientific databases.  Library Assistants are also responsible 
for maintaining the publications catalog systems.

Skills/Knowledge

  -- Ability to communicate effectively.
  -- Ability to use computers to conduct data searches and for word 
     processing.
  -- Detail oriented.

Training/Requirements

  -- High school diploma or equivalent.
  -- Possess up to two years of relevant library experience or completion of 
     on-the-job training.

Wage Range:  $12,000 to $20,000 per year

Occupational Codes

DOT:
Library Assistant, 249.367-046

OES:
Library Assistants, etc., 539020



                               INFORMATION SYSTEMS
                           SCIENTIFIC PROGRAMMER ANALYSTS 

What They Do:  Scientific Programmer Analysts design, develop, evaluate and 
modify computer programs to solve scientific or engineering problems and to 
support Research and development efforts.  They analyze existing systems and 
formulate logic for new systems.  Analysts devise logical procedures, prepare 
flow charts, develop coding, perform tests and debug programs.  They are 
responsible for providing documentation for new and existing programs, 
determining system specifications, input and output processes, and hardware 
and software compatibility.

Skills/Knowledge

  -- Analytical skills.
  -- Ability to think logically.
  -- Good communication and interpersonal skills.
  -- Ability to work with abstract concepts and to work accurately under 
     pressure.

Training/Requirements

  -- BS degree in a scientific discipline or equivalent.
  -- Possess up to two years of related experience.

Wage Range:  $24,000 to $50,000 per year

Occupational Codes

DOT:
Programmer-Analyst, 030.162-014

OES:
System Analysts, Elec. Data Processing,     251020



                    PREPARING FOR JOBS IN BIOTECHNOLOGY

Employers have stated that there are many skills and abilities that they 
look for in entry-level workers.  Some of these include the following:

  -- Ability to work as a team member.
  -- General laboratory skills.
  -- English language skills: to communicate and understand written and 
     spoken instructions and directions, conduct record keeping, and 
     maintain log books.
  -- Use of basic math: add, subtract, multiply, and divide using whole 
     numbers, fractions, and decimals; solve problems using percentages, 
     metric system conversions, and ratios.  Highly level technical jobs 
     will require competency in college level mathematics.
  -- Use of computers for word processing, producing spreadsheets, and 
     manipulating data.

  -- Ability to understand and follow instructions such as governmental 
     regulations and company policies relating to safety, production 
     practices and laboratory procedures.
  -- Attention to detail.
  -- Recognition of problems and reporting them.

Students preparing for careers in biotechnology should be prepared to 
complete high school courses such as chemistry, biology, and mathematics.
Laboratory experience and training is especially important to develop the 
basic skills that will be needed on the job or to succeed in course work at 
community college and university levels.  A strong base in the high school 
sciences and mathematics, in addition to the development of communication 
skills, is especially necessary to prepare students for employment if they 
wish to enter the workforce upon graduation from high school.

Some community colleges, industry organizations, and companies have 
established or are attempting to forge partnerships to provide training to 
prospective biotechnology technicians.

Students should work closely with their instructors, counselors and advisers 
throughout their years in high school and college to plan their academic 
programs and to assess their opportunities in the industry.  

Companies may be willing to hire interns, and many will consider interns who 
have completed high school, graduates with associate degrees, and students 
attending community colleges.  

Most biotechnology companies provide in-house training following employment; 
however, it would be more realistic to expect training from a combination of 
sources: employers, colleges and universities, and technical schools. 

For those who are interested in careers as scientists in California, most 
community colleges offer courses in the biological sciences.  Schools in the 
California State University and University of California systems and private 
institutions throughout the state offer numerous courses ranging from 
biology and the biological sciences to biochemistry, bioengineering, and 
biomedical physics to molecular and cellular biology.

Students should be aware that the biotechnology industry continually changes 
as it develops new products.  The mix of workers in the manufacturing stage 
will differ from the worker mix in Research and development.  Some companies 
may eventually specialize in R&D while others may concentrate more on 
manufacturing.  A company specializing in R&D will tend to hire fewer 
workers than a manufacturing facility.  It will also hire mainly scientists, 
engineers, and a small number of technicians to develop and test their 
products.  When a company reaches the manufacturing stage, it then hires 
more workers to staff  technical, clerical, administrative, sales, and 
maintenance positions.



          RELATED ACADEMIC PROGRAMS IN CALIFORNIA COMMUNITY COLLEGES

The following is a list of programs offered in the California Community 
College system in the biological sciences and related areas.  It was 
compiled from the publication California Colleges and Universities-1995  
published by the California Postsecondary Education Commission.  Prospective 
students interested in these programs should contact these schools for 
more detailed information.  This list is not all-inclusive and subject to 
change at any time.


BIOCHEMISTRY
           College of San Mateo
           College of the Siskiyous

BIOLOGICAL AND PHYSICAL SCIENCES
           College of Alameda
           Citrus College
           Los Medanos College
           San Diego City College
           Victor Valley College

BIOLOGICAL TECHNOLOGY/BIOLOGICAL LABORATORY TECHNOLOGY
           Fullerton College

BIOLOGY/BIOLOGICAL SCIENCES
           Allan Hancock College
           Antelope Valley College
           Bakersfield College
           Barstow College
           Butte-Glenn College
           Cabrillo College
           Canada College
           Cero Coso Community College
           Cerritos College
           Chabot College
           Chaffey College
           Citrus College
           College of Alameda
           College of Marin
           College of the Canyons
           College of the Desert
           College of San Mateo
           College of the Redwoods
           College of the Sequoias
           Columbia College
           Compton Community College
           Contra Costa College
           Crafton Hills College
           Cuesta College
           Cuyamaca College
           Cypress College
           Diablo Valley College
           East Los Angeles College
           El Camino College
           Feather River College
           Foothill College
           Fresno City College
           Fullerton College
           Gavilan College
           Glendale Community College
           Golden West College
           Grossmont College
           Hartnell College
           Imperial Valley College
           Kings River Community College
           Las Positas College
           Long Beach City College
           Los Angeles Mission College
           Los Angeles Southwest College
           Los Angeles Valley College
           Mendocino College
           Merced College
           MiraCosta College
           Mission College
           Modesto Junior College
           Monterey Peninsula College
           Moorpark College
           Mt. San Antonio College
           Mt. San Jacinto College
           Orange Coast College
           Oxnard College
           Palo Verde College
           Palomar College
           Pasadena City College
           Porterville College
           Rancho Santiago College
           Riverside Community College
           Saddleback College
           San Bernardino Valley College
           San Diego City College
           San Diego Mesa College
           San Diego Miramar College
           San Francisco City College
           San Joaquin Delta College
           San Jose City College
           Santa Barbara City College
           Santa Monica College
           Santa Rosa Junior College
           Shasta College
           Skyline College
           Solano Community College
           Southwestern College
           Taft College
           West Hills College
           West Los Angeles College
           West Valley College
           Yuba College

BIOMEDICAL ELECTRONIC EQUIPMENT TECHNOLOGY
           Cerritos College
           Los Angeles City College
           Los Angeles Valley College
           Napa Valley College
           San Joaquin Delta College

BIOTECHNOLOGY/BIOTECHNOLOGY Research
           Contra Costa College
           DeAnza College
           MiraCosta College
           San Diego Miramar College
           Skyline College
           Vista College

LABORATORY TECHNOLOGY
           Merced College

MEDICAL LABORATORY TECHNOLOGY
           Fresno City College
           San Diego Mesa College
           College of the Siskiyous

MEDICAL TECHNOLOGY
           East Los Angeles City College
           Fullerton College

MICROBIOLOGY
           Compton Community College
           Crafton Hills College
           Foothill College
           Fullerton College
           Rancho Santiago College
           Riverside City College
           Shasta College
           College of the Siskiyous
           Southwestern College


SOURCES OF ADDITIONAL INFORMATION

New York Biotechnology Association, Inc.
25 East Loop Road
Stony Brook, NY 11790
(516) 444-8895
http://www.nyba.org/

Bay Area Bioscience Center
1300 Clay Street, Suite 320
Oakland, CA 94612
(510) 874-1464
http://babc.bio.com/

Biotechnology Industry Organization
1625 K Street, N.W.,  Suite 1100
Washington, DC 20006
(202) 857-0244
http://www.bio.org/welcome.html

Education Development Center, Inc.
55 Chapel Street
Newton, MA 02158-1060
(617) 969-7100
http://www.edc.org/

American Society for Biochemistry and Molecular Biology
9650 Rockville Pike
Bethesda, MD 20814-3996
(301) 53300-7145

American Society for Microbiology
Office of Education and Training-Career Information
1325 Massachusetts Avenue, NW
Washington, DC 20005
(202) 737-3600
http://www.asmusa.org/

BIBLIOGRAPHY

Biotechnicians:  Employment Projections and Skills Requirements, 
BioQuest, Inc., San Francisco, California, 1993

Biotechnology Industry Training Needs, The Resource Group, Riverside, 
  California, 1995

Biotechnology:  The Choice for Your Future, Biotechnology Industry 
  Organization, Washington, D.C., 1991.

"California Bioscience Industry," Bay Area Bioscience Reports, Spring 1993, 
  Bay Area Bioscience Center, Oakland, California

California Colleges and Universities-1995, California Postsecondary 
      Education Commission, Sacramento, California, 1995.

Cony, Ann, "Calgene Competitor Patiently Waiting for the Ripe Moment," 
  Sacramento Bee, October 6, 1993.

The Economist, "Predictors of Global Famine Have Had to Eat Their Words," 
  Sacramento Bee, June 18, 1995.

The Emerging Bioscience Skills Gap, Bay Area Bioscience Center and the Bay 
  Area Council, Oakland, California, 1991.

Gateway to the Future: Skill Standards for the Bioscience Industry, 
  Education Development Center, Inc., Newton, Mass., 1995

Hall, Carl T., "Making Friends With Frankenfish," San Francisco Examiner and 
  Chronicle, June 18, 1995.

Hall, Carl. T., "Chiron Leads The Rebound in Biotechnology," San Francisco 
  Chronicle, August 14, 1955.

Minuteman Regional  Vocational Technical School District Biotechnology Task 
  Force, Biomanufacturing in Massachusetts: An Assessment and 
  Educational Analysis, Massachusetts State Department of Education, 
  Lexington, Mass., 1992

Seymour, Patricia, Opportunities in Biotechnology, New York Biotechnology 
  Association, Inc., Stony Brook, N.Y., 1994.

Yund, Mary Alice, Bioscience White Paper, NOVA Private Industry Council, 
  Sunnyvale, Calif., 1995.


Source:  State of California, Employment Development Department, 
         Labor Market Information Division, Information Services Group, 
         (916) 262-2162.
Note:  This is NOT a job opening.  The purpose of this occupational guide is to provide you with useful information to help you make career decisions.   If you are searching for a job, go to:


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